Apolipoprotein C-III is an amyloid-β-binding protein and an early marker for Alzheimer's disease.

Abstract

It has been demonstrated that peripheral injection of anti-amyloid-β (Aβ) antibodies to patients with Alzheimer's disease (AD) and AD transgenic mice facilitate Aβ clearance. We hypothesized that peripheral circulating Aβ-binding proteins also possess the ability to enhance Aβ clearance and the levels of circulating Aβ-binding proteins could serve as early… (More)
DOI: 10.3233/JAD-140111

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