Apolipoprotein B gene polymorphisms and serum lipids: meta-analysis of the role of genetic variation in responsiveness to diet.

@article{Rantala2000ApolipoproteinBG,
  title={Apolipoprotein B gene polymorphisms and serum lipids: meta-analysis of the role of genetic variation in responsiveness to diet.},
  author={Maire Rantala and Tapio T. Rantala and Markku J. Savolainen and Yechiel Friedlander and Yrj{\"o} Antero Kes{\"a}niemi},
  journal={The American journal of clinical nutrition},
  year={2000},
  volume={71 3},
  pages={713-24}
}
BACKGROUND The genetic variance determining plasma lipid and lipoprotein concentrations may modify individual responsiveness to alterations in dietary fat and cholesterol content. OBJECTIVE The aim was to examine the role of apolipoprotein (apo) B DNA polymorphisms in responsiveness of plasma lipids and lipoproteins to diet. DESIGN A controlled dietary intervention study was conducted in 44 healthy, middle-aged subjects with a 3-mo baseline, a 1-mo fat-controlled, a 1-mo high-fat, and a 1… CONTINUE READING
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