Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.

@article{Chen1987ApolipoproteinBI,
  title={Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.},
  author={S H Chen and Gilbert Habib and C. Y. Yang and Zei W Gu and Byung Rho Lee and S A Weng and Steven R. Silberman and Shengjian Cai and J. P. Deslypere and Maryvonne Rosseneu},
  journal={Science},
  year={1987},
  volume={238 4825},
  pages={363-6}
}
The primary structure of human apolipoprotein (apo) B-48 has been deduced and shown by a combination of DNA excess hybridization, sequencing of tryptic peptides, cloned complementary DNAs, and intestinal messenger RNAs (mRNAs) to be the product of an intestinal mRNA with an in-frame UAA stop codon resulting from a C to U change in the codon CAA encoding Gln2153 in apoB-100 mRNA. The carboxyl-terminal Ile2152 of apoB-48 purified from chylous ascites fluid has apparently been cleaved from the… CONTINUE READING