Apolipoprotein A-I as a candidate serum marker for the response to lithium treatment in bipolar disorder.

@article{Sussulini2011ApolipoproteinAA,
  title={Apolipoprotein A-I as a candidate serum marker for the response to lithium treatment in bipolar disorder.},
  author={Alessandra Sussulini and Hassan Dihazi and Cl{\'a}udio Eduardo Muller Banzato and Marco A. Z. Arruda and Walter Stuehmer and Hannelore Ehrenreich and Olaf Jahn and Hartmut D. Kratzin},
  journal={Proteomics},
  year={2011},
  volume={11 2},
  pages={261-9}
}
The molecular basis of bipolar disorder (BD) is still unknown as is the mechanism through which lithium, the therapy of choice, exerts its effects in treatment of BD. So far, no biomarkers exist to facilitate diagnosis of BD or treatment evaluation. To investigate whether BD and its treatment with lithium leaves a characteristic signature in the serum proteome, we used SELDI-TOF MS to analyze individual serum samples from BD patients treated with lithium (BD-plus-Li, n=15) or other drugs (BD… CONTINUE READING
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