Apolipoprotein ε4 Is Associated with Lower Brain Volume in Cognitively Normal Chinese but Not White Older Adults

@inproceedings{Yokoyama2015ApolipoproteinI,
  title={Apolipoprotein ε4 Is Associated with Lower Brain Volume in Cognitively Normal Chinese but Not White Older Adults},
  author={Jennifer S Yokoyama and Allen K. L. Lee and Leonel Tadao Takada and Edgar Busovaca and Luke W Bonham and Steven Z. Chao and Marian M Tse and Jing He and Christopher G. Schwarz and Owen T. Carmichael and Brandy R. Matthews and Anna M. Karydas and Michael W Weiner and Giovanni Coppola and Charles S Decarli and Bruce L. Miller and Howard J. Rosen},
  booktitle={PloS one},
  year={2015}
}
Studying ethnically diverse groups is important for furthering our understanding of biological mechanisms of disease that may vary across human populations. The ε4 allele of apolipoprotein E (APOE ε4) is a well-established risk factor for Alzheimer's disease (AD), and may confer anatomic and functional effects years before clinical signs of cognitive decline are observed. The allele frequency of APOE ε4 varies both across and within populations, and the size of the effect it confers for… CONTINUE READING
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The effects of apolipoprotein E on non-impaired cognitive functioning: A meta-analysis

  • WisdomNM, JL Callahan, KA Hawkins
  • Neurobiol Aging
  • 2011

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