Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

@article{Helgadottir2012ApolipoproteinaGS,
  title={Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.},
  author={Anna Helgadottir and S{\'o}lveig Gr{\'e}tarsd{\'o}ttir and Gudmar Thorleifsson and H. Spangsberg Holm and Riyaz S. Patel and Th{\'o}rarinn Gudnason and G T Jones and Andr{\'e} M. van Rij and Danny J. Eapen and Annette F. Baas and David-Alexandre Tr{\'e}gou{\"e}t and Pierre-Emmanuel Morange and Joseph Emmerich and Bengt Lindblad and Anders Gotts{\"a}ter and Lambertus A Kiemeny and Jes S. Lindholt and Natzi Sakalihasan and Robert E. Ferrell and David J. Carey and James R. Elmore and Philip S. Tsao and Niels Grarup and Torben W. J{\o}rgensen and Daniel Witte and Torben Hansen and Oluf Pedersen and Roberto Pola and Eleonora Gaetani and Hulda Bra Magnadottir and Cisca Wijmenga and Gerard Tromp and Antti Ronkainen and Ynte M Ruigrok and Jan D. Blankensteijn and Thomas M{\"u}ller and Philip S Wells and Javier Corral and Jos{\'e} Manuel Soria and Juan Carlos Souto and John F. Peden and Shapour Jalilzadeh and Bongani M. Mayosi and Bernard D Keavney and Rona J. Strawbridge and Maria Sabater-Lleal and Karl Gertow and Damiano Baldassarre and Kristiina Nyyss{\"o}nen and Rainer Rauramaa and Andries J. Smit and Elmo Mannarino and Philippe Giral and Elena Tremoli and Ulf de Faire and Steve E Humphries and Anders Hamsten and Vilhelm{\'i}na Haraldsd{\'o}ttir and Isleifur Olafsson and Magn{\'u}s Karl Magn{\'u}sson and Nilesh J. Samani and Allan I. Levey and Hugh S. Markus and Konstantinos Kostulas and Martin Dichgans and Klaus Berger and Gregor Kuhlenbaeumer and E. Bernd Ringelstein and Monika Stoll and Udo Seedorf and Peter M. Rothwell and Janet T. Powell and Helena Kuivaniemi and Pall T Onundarson and Einar M{\'a}r Valdimarsson and Stefan E. Matthiasson and Daniel Fannar Gudbjartsson and Guðmundur Thorgeirsson and Arshed A Quyyumi and H. V. Watkins and Martin Farrall and Unnur Thorsteinsdottir and K{\'a}ri Stef{\'a}nsson},
  journal={Journal of the American College of Cardiology},
  year={2012},
  volume={60 8},
  pages={
          722-9
        }
}
OBJECTIVES The purpose of this study is investigate the effects of variants in the apolipoprotein(a) gene (LPA) on vascular diseases with different atherosclerotic and thrombotic components. BACKGROUND It is unclear whether the LPA variants rs10455872 and rs3798220, which correlate with lipoprotein(a) levels and coronary artery disease (CAD), confer susceptibility predominantly via atherosclerosis or thrombosis. METHODS The 2 LPA variants were combined and examined as LPA scores for the… CONTINUE READING
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Structure, function, and genetics of lipoprotein (a).

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Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

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