Apolipoprotein(a) and ischaemic heart disease in familial hypercholesterolaemia

@article{Wiklund1990ApolipoproteinaAI,
  title={Apolipoprotein(a) and ischaemic heart disease in familial hypercholesterolaemia},
  author={O. Wiklund and S. Olofsson and G. Fager and G. Bondjers and L. Berglund},
  journal={The Lancet},
  year={1990},
  volume={335},
  pages={1360-1363}
}
Serum concentrations of apolipoprotein(a) were measured in patients with heterozygous familial hypercholesterolaemia. The levels in 47 patients were a median of 2.5 times higher than those in controls matched for age and sex (240 [range 25-1245] vs 97 [7-1040] mg/l). Among patients with familial hypercholesterolaemia apo(a) levels were higher in those with (n = 48) than in those without (n = 72) ischaemic heart disease (283 [18-1245] vs 144 [7-741] mg/l); both in univariate and multivariate… Expand
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