Apocynin: chemical and biophysical properties of a NADPH oxidase inhibitor.

Abstract

Apocynin is the most employed inhibitor of NADPH oxidase (NOX), a multienzymatic complex capable of catalyzing the one-electron reduction of molecular oxygen to the superoxide anion. Despite controversies about its selectivity, apocynin has been used as one of the most promising drugs in experimental models of inflammatory and neurodegenerative diseases… (More)
DOI: 10.3390/molecules18032821

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