ApoA-II directs morphogenetic movements of zebrafish embryo by preventing chromosome fusion during nuclear division in yolk syncytial layer.

@article{Zhang2011ApoAIIDM,
  title={ApoA-II directs morphogenetic movements of zebrafish embryo by preventing chromosome fusion during nuclear division in yolk syncytial layer.},
  author={Ting Zhang and Shaohua Yao and Ping Wang and Chaoran Yin and Chun Lei Xiao and Meilin Qian and Donghui Liu and Lemin Zheng and Wentong Meng and Hongyan Zhu and Jin Liu and Hong Xu and Xianming Mo},
  journal={The Journal of biological chemistry},
  year={2011},
  volume={286 11},
  pages={
          9514-25
        }
}
The high density lipoprotein (HDL) represents a class of lipid- and protein-containing particles and consists of two major apolipoproteins apoA-I and apoA-II. ApoA-II has been shown to be involved in the pathogenesis of insulin resistance, adiposity, diabetes, and metabolic syndrome. In embryo, apoa2 mRNAs are abundant in the liver, brain, lung, placenta, and in fish yolk syncytial layer (YSL), suggesting that apoa2 may perform a function during embryonic development. Here we find out that… CONTINUE READING

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ApoA-II Controls YSL Organization for Embryogenesis

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