Aplastic anemia: immunosuppressive therapy in 2010

@article{Risitano2011AplasticAI,
  title={Aplastic anemia: immunosuppressive therapy in 2010},
  author={A. Risitano and F. Perna},
  journal={Pediatric Reports},
  year={2011},
  volume={3}
}
Acquired aplastic anemia (AA) is the typical bone marrow failure syndrome characterized by an empty bone marrow; an immune-mediated pathophysiology has been demonstrated by experimental works as well as by clinical observations. Immunusuppressive therapy (IST) is a key treatment strategy for aplastic anemia; since 20 years the standard IST for AA patients has been anti-thymocyte globuline (ATG) plus cyclosporine A (CyA), which results in response rates ranging between 50% and 70%, and even… Expand
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