Apixaban in the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation.

@article{PujadasMestres2013ApixabanIT,
  title={Apixaban in the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation.},
  author={Lluis Pujadas-Mestres and Gin{\'e}s Escolar and Eduardo Arellano-Rodrigo and Ana Mar{\'i}a Gal{\'a}n},
  journal={Drugs of today},
  year={2013},
  volume={49 7},
  pages={425-36}
}
Conventional anticoagulant therapies can significantly reduce the risk of stroke and related complications in patients with atrial fibrillation (AF). Classic oral anticoagulants based on vitamin K antagonism have shown effectiveness in the prevention of thromboembolic complications in this clinical setting. Unfortunately, vitamin K antagonists that have shown effectiveness in the prevention of thromboembolic complications in patients with nonvalvular AF hold inherent limitations including… CONTINUE READING