Apiosporamide, a new antifungal agent from the coprophilous fungus Apiospora montagnei.

@article{Alfatafta1994ApiosporamideAN,
  title={Apiosporamide, a new antifungal agent from the coprophilous fungus Apiospora montagnei.},
  author={A A Alfatafta and James B Gloer and James A Scott and David W. Malloch},
  journal={Journal of natural products},
  year={1994},
  volume={57 12},
  pages={1696-702}
}
Bioassay-guided fractionation of an EtOAc extract from the mycelium of the coprophilous fungus Apiospora montagnei has furnished a new antifungal metabolite, named apiosporamide [1], and the known dihydroisocoumarin cis-(3R,4R)-4-hydroxymellein [4]. The structure of 1 was assigned on the basis of HMBC, HMQC, NOESY, and hrms data. Elucidation of the structure was complicated by the fact that several nmr signals appeared only under certain conditions.