Apigenin inhibits enterovirus 71 replication through suppressing viral IRES activity and modulating cellular JNK pathway.

@article{Lv2014ApigeninIE,
  title={Apigenin inhibits enterovirus 71 replication through suppressing viral IRES activity and modulating cellular JNK pathway.},
  author={Xiaowen Lv and Min Qiu and Deyan Chen and Nan Zheng and Yu Jin and Zhiwei Wu},
  journal={Antiviral research},
  year={2014},
  volume={109},
  pages={30-41}
}
Enterovirus 71 (EV71) is a member of genus Enterovirus in Picornaviridae family, which is one of the major causative agents for hand, foot and mouth disease (HFMD), and sometimes associated with severe central nervous system diseases in children. Currently there are no effective therapeutic medicines or vaccines for the disease. In this report, we found that apigenin and luteolin, two flavones that differ only in the number of hydroxyl groups could inhibit EV71-mediated cytopathogenic effect… CONTINUE READING
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