Apigenin-induced nitric oxide production involves calcium-activated potassium channels and is responsible for antiangiogenic effects.

Abstract

BACKGROUND The dietary flavonoid apigenin (Api) has been demonstrated to exert multiple beneficial effects upon the vascular endothelium. The aim of this study was to examine whether Ca(2+)-activated K(+) channels (K(Ca)) are involved in endothelial nitric oxide (NO) production and antiangiogenic effects. METHODS Endothelial NO generation was monitored… (More)

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Cite this paper

@article{Erdoan2007ApigenininducedNO, title={Apigenin-induced nitric oxide production involves calcium-activated potassium channels and is responsible for antiangiogenic effects.}, author={Ali Riza Erdoğan and Astrid Kerstin Most and Barbara C Wienecke and Annett Fehsecke and C Leckband and Richard F. Voss and Mathias T Grebe and Harald Tillmanns and C. A. Schaefer and Christian Kuhlmann}, journal={Journal of thrombosis and haemostasis : JTH}, year={2007}, volume={5 8}, pages={1774-81} }