Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells

@article{Korga2019ApigeninAH,
  title={Apigenin and hesperidin augment the toxic effect of doxorubicin against HepG2 cells},
  author={A. Korga and M. Ostrowska and A. J{\'o}zefczyk and Magdalena Iwan and R. W{\'o}jcik and G. Zg{\'o}rka and M. Herbet and Gemma Gomez Vilarrubla and J. Dudka},
  journal={BMC Pharmacology \& Toxicology},
  year={2019},
  volume={20}
}
BackgroundHepatocellular carcinoma (HCC) is one of the most common malignancies, with an increasing incidence. Despite the fact that systematic chemotherapy with a doxorubicin provides only marginal improvements in survival of the HCC patients, the doxorubicin is being used in transarterial therapies or combined with the target drug – sorafenib. The aim of the study was to evaluate the effect of natural flavonoids on the cytotoxicity of the doxorubicin against human hepatocellular carcinoma… Expand
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Protective effect of myricetin, apigenin, and hesperidin pretreatments on cyclophosphamide-induced immunosuppression
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