Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium.

@article{McCormick1998ApicalSO,
  title={Apical secretion of a pathogen-elicited epithelial chemoattractant activity in response to surface colonization of intestinal epithelia by Salmonella typhimurium.},
  author={Beth Ann McCormick and Charles A Parkos and Sean P Colgan and D K Carnes and James L. Madara},
  journal={Journal of immunology},
  year={1998},
  volume={160 1},
  pages={455-66}
}
Modeling Salmonella-epithelial cell interaction in vitro has led to the realization that epithelial cells are crucial in orchestrating neutrophil (PMN) responses, in part by stimulating basolateral release of epithelial chemokines, including IL-8. However, such basolaterally released chemokines, while likely important in orchestration of PMN movement across the subepithelial matrix, are unlikely to be responsible for the final step of transepithelial migration of PMN and entry into the apical… CONTINUE READING

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1993.Salmonella typhimuriumattachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils

  • B. A. McCormick, S. P. Colgan, C. D. Archer, S. I. Miller, J. L. Madara
  • J. Cell Biol
  • 1993
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