Apical expression of herpes simplex virus type 2 glycoproteins in human neuroblastoma cells.

@article{Nielsen1991ApicalEO,
  title={Apical expression of herpes simplex virus type 2 glycoproteins in human neuroblastoma cells.},
  author={Ludvig Nikolaj Nielsen and Richard J. Whitley and Subroto B Chatterjee},
  journal={Virology},
  year={1991},
  volume={185 2},
  pages={
          908-10
        }
}
The expression of herpes simplex virus type 2 (HSV-2) glycoproteins on the surface of human neuroblastoma cells has been investigated using Millipore Millicell culture plate inserts. Utilizing a modified radioimmunoassay, we learned that glycoproteins B, C, D, E, and I were expressed predominantly on the apical membrane domain of the infected neuroblastoma cells. The unidirectional transport of HSV-2 glycoproteins was substantiated by the analysis of extracellular glycoproteins released from… CONTINUE READING

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