Corpus ID: 25019565

Apical cell shape changes during Drosophila imaginal leg disc elongation: a novel morphogenetic mechanism.

@article{Condic1991ApicalCS,
  title={Apical cell shape changes during Drosophila imaginal leg disc elongation: a novel morphogenetic mechanism.},
  author={M. Condic and D. Fristrom and J. Fristrom},
  journal={Development},
  year={1991},
  volume={111 1},
  pages={
          23-33
        }
}
Imaginal discs of Drosophila are simple epithelial tissues that undergo dramatic changes in shape during metamorphosis, including elongation to form adult appendages such as legs and wings. We have examined the cellular basis of leg disc morphogenesis by staining filamentous actin to outline cell boundaries in discs and observing cell shapes with scanning confocal laser microscopy (SCLM). Surprisingly, we found that prior to the onset of morphogenesis, cells in the dorsal-lateral regions of leg… Expand
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