Apical and basolateral conductance in cultured A6 cells

  title={Apical and basolateral conductance in cultured A6 cells},
  author={M. Granitzer and T. Leal and W. Nagel and J. Crabb{\'e}},
  journal={Pfl{\"u}gers Archiv},
  • M. Granitzer, T. Leal, +1 author J. Crabbé
  • Published 2004
  • Chemistry, Medicine
  • Pflügers Archiv
  • Confluent monolayers of the cultured renal distal tubule cell line (A6) were impaled with microelectrodes under short-circuit conditions. Specific membrane conductances were calculated from equivalent circuit equations. Transport properties of the apical and basolateral membranes were investigated during control conditions and short-term increases in basolateral potassium concentration [K+] from 2.5 to 20 mmol/l, with or without 0.5 mmol/l Ba2+ at the basolateral side. As in most other… CONTINUE READING

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