Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats.

  title={Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats.},
  author={Kalamegam Gauthaman and P. G. Adaikan and Rout Nutan Prasad},
  journal={Life sciences},
  volume={71 12},

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The furostenol glycoside fraction of Tribulus terrestris exhibited good aphrodisiac properties and was found to increase orientational activity parameters such as licking and ano-and genital grooming and decreased climbing and nongential grooming by male rats indicating increased sexual stimulation and lack of interest toward external environment after treatment with TT-FG.
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Protodioscin from herbal plant Tribulus terrestris L improves the male sexual functions, probably via DHEA
A significant increase of DHEA-S levels in diabetic and non-di diabetic subjects after treatment, and a significant increase in the frequency of successful intercourse by 60% in both the diabetic andNon-diabetic groups with or without ED.
Proerectile pharmacological effects of Tribulus terrestris extract on the rabbit corpus cavernosum.
The relaxant responses to acetylcholine, nitroglycerin and EFS and the lack of such effect on the contractile response to noradrenaline and histamine indicate that PTN has a proerectile activity, which may account for its claims as an aphrodisiac.
Activity of certain fractions of Tribulus terrestris fruits against experimentally induced urolithiasis in rats.
An ethanolic extract of the fruits of T. terrestris showed significant dose dependent protection against uroliths induced by glass bead implantation in albino rats, and fractionation lead to decreased activity.
Effects of castration and exogenous testosterone supplementation in an animal model of penile erection.
Dihydrotestosterone is the active androgen in the maintenance of nitric oxide-mediated penile erection in the rat.
Results show that DHT is the active androgen in the prevention of erectile failure seen in castrated rats, and suggest that this effect may be mediated, at least partially, by changes in nitric oxide synthase levels in the penis.
Castration may not affect the penile erection ability in terms of peripheral neurocavernous mechanism in dogs.
Activation of sexual reflexes of male rats by dihydrotestosterone but not estrogen
  • B. Hart
  • Biology, Psychology
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  • 1979
Effects of castration and androgen replacement on erectile function in a rabbit model.
The results of this study demonstrate that androgen deprivation alters the functional responses and structure of erectile tissue.
[Effects of testosterone on smooth muscle in the isolated rabbit corpus cavernosum penis].
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  • 1993
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Effects of castration on adrenergic, cholinergic and nonadrenergic, noncholinergic responses of isolated corpus cavernosum from rabbit.
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