Aphrodisiac evaluation in non‐copulator male rats after chronic administration of Eurycoma longifolia Jack *

@article{Ang2001AphrodisiacEI,
  title={Aphrodisiac evaluation in non‐copulator male rats after chronic administration of Eurycoma longifolia Jack *},
  author={Hooi Hoon Ang and T H Ngai},
  journal={Fundamental \& Clinical Pharmacology},
  year={2001},
  volume={15}
}
  • H. Ang, T. Ngai
  • Published 1 August 2001
  • Medicine
  • Fundamental & Clinical Pharmacology
The aphrodisiac effect of Eurycoma longifolia Jack (0.5 g/kg) was evaluated in noncopulator male rats using an electrical cage. Fractions of E. longifolia Jack decreased the hesitation time of noncopulator male rats, throughout the investigation period. Furthermore, it possessed a transient increase in the percentage of the male rats responding to the right choice, more than 50% of the male rats scored ‘right choice’ after 3 weeks post‐treatment and the effect became more prominent after 8… 
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PHASE I DRUG METABOLISM STUDY OF THE STANDARDISED EXTRACT OF EURYCOMA LONGIFOLIA (TAF­273) IN RAT HEPATOCYTES
Eurycoma longifolia is widely used as an alternative medicine by society. Some patients may use a herb‐drug treatment while taking prescribed medication. It is possible that one substance may alter
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References

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Extracts of EURYCOMA LONGIFOLIA Jack (Simaroubaceae) have been tested for antiplasmodial activity against a multi-drug resistant Thailand strain (K-1) of PLASMODIUM FALCIPARUM IN VITRO.
In vitro antimalarial activity of quassinoids from Eurycoma longifolia against Malaysian chloroquine-resistant Plasmodium falciparum isolates.
Three quassinoids from the roots of Eurycoma longifolia Jack were evaluated for antimalarial activity against nine Plasmodium falciparum isolates obtained from patients infected with
Effect of 7-day daily replacement of culture medium containing Eurycoma longifolia Jack constituents on the Malaysian Plasmodium falciparum isolates.
TLDR
Six Malaysian chloroquine-resistant Plasmodium falciparum isolates were cultured in vitro following the candle-jar method and results showed that the antimalarial activity of Eurycoma longifolia Jack was dose-dependent and reached a maximum of < 50% at 0.07-5.00 micrograms ml-1 after 1 day post-treatment.
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TLDR
By bioactivity-directed fractionation, five cytotoxic constituents have been characterized from the roots of Eurycoma longifolia and compounds 5 and 7 were found to demonstrate significant antimalarial activity as judged by studies conducted with cultured Plasmodium falciparum strains.
Cytotoxic Quassinoids and Tirucallane-Type Triterpenes from the Woods of Eurycoma longifolia.
New cytostatic quassinoids, 6α-hydroxyeurycomalactone (1), longilactone (2) and 14, 15β-dihydroxyklaineanone (3) were isolated from the woods of Eurycoma longifolia (Simaroubaceae) with three
QUANTITATIVE MEASUREMENT OF SEXUAL RECEPTIVITY IN FEMALE RATS 1)
Thirty-four intact female rats were observed at hourly intervals in standardized tests designed to reveal the presence and intensity of sexual receptivity. The onset of this condition was related to
Lordosis reflex intensity in rats in relation to the estrous cycle, ovariectomy, estrogen administration and mating behavior.
TLDR
Lordosis in response to manual palpation of the flanks and perineum was markedly facilitated by simultaneously probing the vaginal cervix, and intensity and probability of occurrence varied significantly in relation to the estrous cycle.
Sexual motivation in the female rat after testosterone treatment.
TLDR
It was a consistent finding in the three different methods used that TP 1 mg/kg induced a significant increase in the willingness of ovariectomized rats to seek contact with a sexually active male.
A quassinoid glycoside from the roots of Eurycoma longifolia
Abstract A new quassinoid glycoside, eurycomanol-2-O-β- d -glycopyranoside, and eurycomanol have been isolated as antimalarial components of Eurycoma longifolia.
Sexual motivation in the estrogen treated ovariectomized rat.
TLDR
It is concluded that estradiol treatment of the ovariectomized female rat induces an urge to make sexual contact with a vigorous male.
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