Apelin has in vivo inotropic effects on normal and failing hearts.

Abstract

BACKGROUND Apelin has been shown ex vivo to be a potent cardiac inotrope. This study was undertaken to evaluate the in vivo effects of apelin on cardiac function in native and ischemic cardiomyopathic rat hearts using a novel combination of a perivascular flow probe and a conductance catheter. METHODS AND RESULTS Native rats (n =32) and rats in heart… (More)

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Cite this paper

@article{Berry2004ApelinHI, title={Apelin has in vivo inotropic effects on normal and failing hearts.}, author={Mark F. Berry and Timothy J. Pirolli and Vasant Jayasankar and Jeffrey W Burdick and Kevin J. Morine and Timothy J. Gardner and Young-min Woo}, journal={Circulation}, year={2004}, volume={110 11 Suppl 1}, pages={II187-93} }