Apelin 13: a novel approach to enhance efficacy of hypoxic preconditioned mesenchymal stem cells for cell therapy of diabetes.

@article{Mottaghi2012Apelin1A,
  title={Apelin 13: a novel approach to enhance efficacy of hypoxic preconditioned mesenchymal stem cells for cell therapy of diabetes.},
  author={Sayeh Mottaghi and Bagher Larijani and Ali Mohammad Sharifi},
  journal={Medical hypotheses},
  year={2012},
  volume={79 6},
  pages={717-8}
}
Recent studies have proposed cell therapy as an alternative therapeutic strategy for many disease states such as diabetes mellitus. Among different cell types mesenchymal stem cells (MSC) have attracted a significant attention based on their intriguing potentials. However MSC therapy is limited as a large portion of transplanted cells undergo apoptosis after transplantation. Therefore, proposing a strategy to overcome this obstacle may be of great value. Recent studies have shown that hypoxia… CONTINUE READING