Apathy and Parkinson's disease.

  title={Apathy and Parkinson's disease.},
  author={Sergio E. Starkstein and Simone Brockman},
  journal={Current treatment options in neurology},
  volume={13 3},
OPINION STATEMENT Apathy, a frequent finding in Parkinson's disease (PD), is significantly associated with depression and dementia. Few studies have examined the efficacy of psychotropic or psychological treatments of apathy in PD, and adequate randomized controlled trials are still lacking. There is anecdotal evidence that dopaminergic agonists may be a useful treatment modality. Levodopa may improve the loss of motivation in the "off" motor state, and dopaminergic agonists could be useful to… CONTINUE READING


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