Aortic wave intensity analysis of ventricular-vascular interaction during incremental dobutamine infusion in adult sheep.

@article{Penny2008AorticWI,
  title={Aortic wave intensity analysis of ventricular-vascular interaction during incremental dobutamine infusion in adult sheep.},
  author={Daniel J. Penny and Jonathan P. Mynard and Joseph J. Smolich},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2008},
  volume={294 1},
  pages={H481-9}
}
This study undertook a detailed examination of the ventricular-vascular interaction of the predominant beta-adrenergic agonist dobutamine using wave intensity analysis. Eight anesthetized open-chest ewes were instrumented with an aortic micromanometer to measure central aortic blood pressure (P) and an ultrasonic flow probe to obtain ascending aortic blood velocity (U). Hemodynamics were recorded during incremental dobutamine infusion (0.5, 1, 2.5, 5, 7.5, and 10 microg.kg(-1).min(-1)). Wave… CONTINUE READING
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The pharmacology of dobutamine

  • Ruffolo RR
  • Am J Med Sci 294:
  • 1987
Highly Influential
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