Aortic valve stenosis: an active atheroinflammatory process.

  title={Aortic valve stenosis: an active atheroinflammatory process.},
  author={Satu Helske and Markku M Kupari and Ken A. Lindstedt and Petri T. Kovanen},
  journal={Current opinion in lipidology},
  volume={18 5},
PURPOSE OF REVIEW To summarize the current understanding of the pathobiology of aortic valve stenosis and portray the major advances in this field. RECENT FINDINGS Stenotic aortic valves are characterized by atherosclerosis-like lesions, consisting of activated inflammatory cells, including T lymphocytes, macrophages, and mast cells, and of lipid deposits, calcific nodules, and bone tissue. Active mediators of calcification and cells with osteoblast-like activity are present in diseased… CONTINUE READING


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