Aortic changes in cynomolgus monkeys fed high-fat diets (long-term study).

Two diets containing either a lard-corn oil mixture (LCO) or partially hydrogenated herring oil (PHHO) were fed to cynomolgus monkeys (Macaca fascicularis) for up to 30 months. Serum cholesterol values rose to 180 mg/dl in the LCO-group and to 260 mg/dl in the PHHO-group. Serum lipoprotein concentrations were normal in the LCO-group, but PHHO-fed monkeys… CONTINUE READING