Aortic abnormalities in males with Alport syndrome.

@article{Kashtan2010AorticAI,
  title={Aortic abnormalities in males with Alport syndrome.},
  author={Clifford E. Kashtan and Yoav Segal and Frances Flinter and David Makanjuola and Jay-Sen Gan and Terry J. Watnick},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2010},
  volume={25 11},
  pages={
          3554-60
        }
}
  • Clifford E. Kashtan, Yoav Segal, +3 authors Terry J. Watnick
  • Published in
    Nephrology, dialysis…
    2010
  • Medicine
  • BACKGROUND There have been isolated case reports of arterial disease in males with Alport syndrome (AS), a systemic disorder of Type IV collagen. In this paper, we describe five new cases of AS associated with significant aortic disease including dissection and aneurysm. METHODS We present brief clinical descriptions of five males with AS and aortic disease. We performed immunohistochemical analysis of the expression of the α5 chain of Type IV collagen in skin basement membranes from a… CONTINUE READING

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    Alport Syndrome in Women and Girls.

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