Anxioselective anxiolytics: on a quest for the Holy Grail.

  • Phil Skolnick
  • Published 2012 in Trends in pharmacological sciences


The discovery of benzodiazepine receptors provided the impetus to discover and develop anxioselective anxiolytics ('Valium without the side effects'). The market potential for an anxioselective based on the γ-aminobutyric acid A (GABA(A)) receptor resulted in clinical trials of multiple compounds. In contrast to the anxioselective profile displayed in… (More)
DOI: 10.1016/


Cite this paper

@article{Skolnick2012AnxioselectiveAO, title={Anxioselective anxiolytics: on a quest for the Holy Grail.}, author={Phil Skolnick}, journal={Trends in pharmacological sciences}, year={2012}, volume={33 11}, pages={611-20} }