Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and alpha1-adrenergic receptor.

@article{Kakui2009AnxiolyticlikePO,
  title={Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and alpha1-adrenergic receptor.},
  author={Nobukazu Kakui and Fumikazu Yokoyama and Miki Yamauchi and Kouichi Kitamura and Taiichiro Imanishi and Takeshi Inoue and Tsukasa Koyama},
  journal={Pharmacology, biochemistry, and behavior},
  year={2009},
  volume={92 3},
  pages={393-8}
}
Mirtazapine is an antidepressant with a unique mechanism of action and has been categorized as a Noradrenergic and Specific Serotonergic Antidepressant (NaSSA). Although numerous clinical trials suggested the usefulness of mirtazapine for not only major depressive disorders but also a variety of anxiety disorders, efficacy studies in animal anxiety models… CONTINUE READING