Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications

@article{Ring2005AnxiolyticlikeAO,
  title={Anxiolytic-like activity of oxytocin in male mice: behavioral and autonomic evidence, therapeutic implications},
  author={R. Ring and J. Malberg and Lisa Potestio and Julia Ping and Steve Boikess and B. Luo and L. Schechter and S. Rizzo and Zia Rahman and S. Rosenzweig-Lipson},
  journal={Psychopharmacology},
  year={2005},
  volume={185},
  pages={218-225}
}
  • R. Ring, J. Malberg, +7 authors S. Rosenzweig-Lipson
  • Published 2005
  • Medicine, Psychology
  • Psychopharmacology
  • RationaleOxytocin (OT) acts as a neuromodulator/neurotransmitter within the central nervous system (CNS) and regulates a diverse range of CNS functions. Notably, evidence from studies in females has revealed an important role for OT in regulating anxiety behavior.ObjectivesThe objective of this study was to examine the effects of OT on both behavioral and autonomic parameters of the anxiety response in male mice using three pharmacologically validated preclinical models of anxiety: the four… CONTINUE READING
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