Anxiolytic effects of GLYX-13 in animal models of posttraumatic stress disorder-like behavior.

Abstract

In the present study, we investigated the effectiveness of GLYX-13, an NMDA receptor glycine site functional partial agonist, to alleviate the enhanced anxiety and fear response in both a mouse and rat model of stress-induced behavioral changes that might be relevant to posttraumatic stress disorder (PTSD). Studies over the last decades have suggested that… (More)
DOI: 10.1177/0269881116645298

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