Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder

  title={Anxiolytic Effects of Flavonoids in Animal Models of Posttraumatic Stress Disorder},
  author={Li-ming Zhang and Jiarong Yao and Yang Li and Kai Li and Hong-xia Chen and You-zhi Zhang and Yun Feng Li},
  journal={Evidence-based Complementary and Alternative Medicine : eCAM},
  • Li-ming Zhang, Jiarong Yao, Y. Li
  • Published 13 December 2012
  • Biology, Psychology
  • Evidence-based Complementary and Alternative Medicine : eCAM
The dysregulation of the serotonergic system has long been recognized as an important factor underlying the pathophysiology of PTSD. To date, SSRIs have already been established as the firstline pharmacotherapeutic agents for treating acute and chronic PTSD. However, SSRIs largely have several disadvantages which limit their utility. Our previous study has also shown that administration of the total flavonoids, isolated from the extract of Xiaobuxin-Tang (XBXT, mild mind-easing decoction… 

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