Anxiolytic-, antidepressant- and anticonvulsant-like effects of the alkaloid montanine isolated from Hippeastrum vittatum

  title={Anxiolytic-, antidepressant- and anticonvulsant-like effects of the alkaloid montanine isolated from Hippeastrum vittatum
  author={A.C.S. da Silva and Jean Paulo de Andrade and Liar M. Bevilaqua and M{\'a}rcia Maria de Souza and Iv{\'a}n Izquierdo and Am{\'e}lia Teresinha Henriques and Jos{\'e} Angelo Silveira Zuanazzi},
  journal={Pharmacology Biochemistry and Behavior},
Effect of isoquinoline alkaloids from two Hippeastrum species on in vitro acetylcholinesterase activity.
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MCE of B. nigra flowers and its fraction possess significant anxiolytic, anthelmintic, anticancer and thrombolytic properties which may be a good candidate for treating these diseases through the determination of bio-active lead compounds.
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Alkaloids from Habranthus tubispathus and H. jamesonii, two Amaryllidaceae with Acetyl- and Butyrylcholinesterase Inhibition Activity
The alkaloids present in these Amaryllidaceae were identified by means of GC-MS analysis and isolated and completely characterized by 1H and 13C NMR spectroscopy, and could be explained by the presence of galanthamine and sanguinine, two potent AChE inhibitors.
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Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family
The present review aims to summarize comprehensively the research that has been published on the Amaryllidaceae alkaloids of montanine-type, which display promising biological properties, especially in vitro cytotoxic activity against different cancerous cell lines.
Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies.
The purpose of this narrative review is to provide an update regarding medicinal plants from the year 2000 to the present to examine the therapeutic potential of these antidepressant-like plants in order to contribute to the development of new therapeutic methods to alleviate the tremendous burden that depression causes worldwide.


Anxiolytic properties of the antipsychotic alkaloid alstonine
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The present results may reflect a correspondence between in vivo and in vitro effects of the essential oil from T. minuta, suggesting its capability to exert a negative modulation on GABAergic function.
Ethopharmacological analysis of the effects of putative ‘anxiogenic’ agents in the mouse elevated plus-maze
Anxioselective properties of 6,3'-dinitroflavone, a high-affinity benzodiazepine receptor ligand.