Anxiogenic-like effects induced by hemopressin in rats.

  title={Anxiogenic-like effects induced by hemopressin in rats.},
  author={Manoela Viar Fogaça and Andreza B. Sonego and Vanessa Rioli and Fabio Cesar Gozzo and Camila S Dale and Emer Suavinho Ferro and Francisco S Guimar{\~a}es},
  journal={Pharmacology, biochemistry, and behavior},
Hemopressin (PVNFKFLSH; HP) is an orally active peptide derived from rat hemoglobin α-chain that could act as an inverse agonist at cannabinoid type 1 receptors (CB1). Here, we aim to investigate possible behavioral effects of HP in male Wistar rats tested in the elevated plus maze (EPM), following HP intraperitoneal (i.p., 0.05 mg/kg), oral (P.O., 0.05 and… CONTINUE READING