Anxiogenic drug administration and elevated plus-maze exposure in rats activate populations of relaxin-3 neurons in the nucleus incertus and serotonergic neurons in the dorsal raphe nucleus.

@article{Lawther2015AnxiogenicDA,
  title={Anxiogenic drug administration and elevated plus-maze exposure in rats activate populations of relaxin-3 neurons in the nucleus incertus and serotonergic neurons in the dorsal raphe nucleus.},
  author={Adam J Lawther and Maverick Clissold and Sherie Ma and Stephen P Kent and Christopher A Lowry and Andrew L Gundlach and Matthew Hale},
  journal={Neuroscience},
  year={2015},
  volume={303},
  pages={270-84}
}
Anxiety is a complex and adaptive emotional state controlled by a distributed and interconnected network of brain regions, and disruption of these networks is thought to give rise to the behavioral symptoms associated with anxiety disorders in humans. The dorsal raphe nucleus (DR), which contains the majority of forebrain-projecting serotonergic neurons, is implicated in the control of anxiety states and anxiety-related behavior via neuromodulatory effects on these networks. Relaxin-3 is the… CONTINUE READING

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…