Anxiogenic activity of intraventricularly administered bradykinin in rats

@article{Bhattacharya1995AnxiogenicAO,
  title={Anxiogenic activity of intraventricularly administered bradykinin in rats},
  author={Salil Kumar Bhattacharya and P. Jagan Mohan Rao and A. P. Sen},
  journal={Journal of Psychopharmacology},
  year={1995},
  volume={9},
  pages={348 - 354}
}
The anxiogenic action of bradykinin was investigated in rats and compared with that of yohimbine, a known anxiogenic agent. Bradykinin (0.5, 1 and 2 μg/rat) was administered intracerebroventricularly (i.c.v.), whereas yohimbine (2 mg/kg) was administered i.p. The experimental methods used were the open- field, elevated plus-maze, social interaction and novelty suppressed feeding latency tests, and estimation of brain tribulin activity in terms of endogenous monoamine oxidase (MAO) A and MAO B… 

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