Anxiety-like behaviour in rats with mononeuropathy is reduced by the analgesic drugs morphine and gabapentin

@article{Roeska2008AnxietylikeBI,
  title={Anxiety-like behaviour in rats with mononeuropathy is reduced by the analgesic drugs morphine and gabapentin},
  author={Kerstin Roeska and Henri N. Doods and Kirsten Arndt and Rolf-Detlef Treede and Angelo Ceci},
  journal={PAIN},
  year={2008},
  volume={139},
  pages={349-357}
}
Anxiety has been described as an important comorbidity in patients suffering from chronic pain. However, in animals the connection between persistent pain and anxiety has hardly been investigated. Therefore, in the current study it was assessed whether chronic pain also causes anxiety-like behaviour in animals and if it can be reversed by analgesic or anxiolytic drugs. Neuropathic pain was induced in rats by partial sciatic nerve ligation (PNL) and chronic constriction injury (CCI). Mechanical… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 32 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Similar Papers

Loading similar papers…