Anxiety-like behavior in crayfish is controlled by serotonin

  title={Anxiety-like behavior in crayfish is controlled by serotonin},
  author={Pascal Fossat and Julien Bacqu{\'e}-Cazenave and Philippe De Deurwaerd{\`e}re and Jean Paul Delbecque and Daniel Cattaert},
  pages={1293 - 1297}
Anxiety, a behavioral consequence of stress, has been characterized in humans and some vertebrates, but not invertebrates. [] Key Result This behavior was correlated with an increase in brain serotonin and was abolished by the injection of the benzodiazepine anxiolytic chlordiazepoxide. Serotonin injection into unstressed crayfish induced avoidance; again, this effect was reversed by injection with chlordiazepoxide. Our results demonstrate that crayfish exhibit a form of anxiety similar to that described in…

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