Anxiety-like behavior in crayfish is controlled by serotonin

@article{Fossat2014AnxietylikeBI,
  title={Anxiety-like behavior in crayfish is controlled by serotonin},
  author={P. Fossat and Julien Bacqu{\'e}-Cazenave and P. De Deurwaerd{\`e}re and J. Delbecque and D. Cattaert},
  journal={Science},
  year={2014},
  volume={344},
  pages={1293 - 1297}
}
Anxiety, a behavioral consequence of stress, has been characterized in humans and some vertebrates, but not invertebrates. [...] Key Result This behavior was correlated with an increase in brain serotonin and was abolished by the injection of the benzodiazepine anxiolytic chlordiazepoxide. Serotonin injection into unstressed crayfish induced avoidance; again, this effect was reversed by injection with chlordiazepoxide. Our results demonstrate that crayfish exhibit a form of anxiety similar to that described in…Expand
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