Anxiety in the rat is associated with decreased release of 5-HT and glycine from the hippocampus.

Abstract

Rats, implanted with dialysis loops in the dorsal hippocampus, were injected with subconvulsant doses of pentylenetetrazole (PTZ 15 and 30 mg/kg) and a 30-min sample collected for high-performance liquid chromatography (HPLC) analysis of amines and amino acids. Immediately after the sampling period they were given a 5-min test in the elevated plus-maze. On… (More)

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Cite this paper

@article{File1987AnxietyIT, title={Anxiety in the rat is associated with decreased release of 5-HT and glycine from the hippocampus.}, author={Sandra E. File and P F Curle and Holly Ann Baldwin and M. J. Neal}, journal={Neuroscience letters}, year={1987}, volume={83 3}, pages={318-22} }