Anxiety disorders

  title={Anxiety disorders},
  author={Brenda W.J.H. Penninx and Daniel S. Pine and Emily A. Holmes and Andreas Reif},
  journal={The Lancet},

Correlates of Quality of Life in Anxiety Disorders: Review of Recent Research

Understanding the underlying factors that contribute to QOL detriments provides important insight into the impact of anxiety disorders and identifies targets for enhancing QOL through treatment.

Neuromodulation Treatments of Pathological Anxiety in Anxiety Disorders, Stressor-Related Disorders, and Major Depressive Disorder: A Dimensional Systematic Review and Meta-Analysis

There is moderate quality evidence for the efficacy of neuromodulation in treating pathological anxiety, and subgroup analyses revealed positive effects for TMS across disorders, and of focal neurommodulation in generalized anxiety disorder and PTSD.

Recent advances in understanding neural correlates of anxiety disorders in children and adolescents

This review highlights recent findings on neural indices related to fear and anxiety that provide novel directions for attempts to create improvements in outcome prediction and treatment, and reviews novel approaches with promise for using such large-scale data to detect clinically relevant, broadly distributed circuitry dysfunction.

Sleep and anxiety: From mechanisms to interventions.

Assessment of anxiety disorders in students starting work with coronavirus patients during a pandemic in Podlaskie Province, Poland

Anxiety among the evaluated students during the COVID-19 pandemic was correlated with many factors, including state anxiety, the self-assessment of professional preparedness for work with coronavirus patients, self-perceived health status, and the assistance of a psychiatrist in the past.

Substance use, microbiome and psychiatric disorders

Health benefits of physical activity for people with mental disorders: From the perspective of multidimensional subjective wellbeing

This paper uses a large scale and nationally representative dataset, Chinese General Social Survey, to empirically examine the role of physical activity in reducing the negative effects of depression

Standard CBT versus integrative and multimodal CBT assisted by virtual-reality for generalized anxiety disorder

Introduction Generalized Anxiety Disorder (GAD) is a prevalent emotional disorder associated with increased dysfunctionality, which has a lasting impact on the individual’s quality of life. Besides



Epidemiology of anxiety disorders in the 21st century

There is no evidence that the prevalence rates of anxiety disorders have changed in the past years, but in cross-cultural comparisons, prevalence rates are highly variable and heterogeneity is due to differences in methodology than to cultural influences.

Major depressive disorder

An overview of the current evidence of major depressive disorder, including its epidemiology, aetiology, pathophysiology, diagnosis and treatment, is provided.

Genetics of Anxiety Disorders

This review will cover recent findings from large-scale genome-wide association studies as well as newer epigenome-wide studies, and discuss prospects for clinical translation of genetic findings and future directions for research.

Long-term disability in anxiety disorders

Various anxiety disorders have different disability levels over 4 years of time, therefore diagnostic distinction is important for treatment focus and anxiety arousal and avoidance behaviour are major predictors for long-term disability in anxiety disorders.

Comorbidity of bipolar and anxiety disorders: An overview of trends in research

An overview of the current trends in research on comorbid anxiety and BDs based on prior reviews and meta-analyses, epidemiological surveys, and large-scale clinical studies finds that at least half of those with BD are likely to develop an anxiety disorder in their lifetimes and a third of them will manifest anxiety disorder at any point of time.


Adaptive defensive engagement during imagery may be compromised by long‐term dysphoria and stress—a phenomenon with implications for prognosis and treatment planning.

Childhood antecedents and risk for adult mental disorders.

How longitudinal research has identified three particular groups of disorders shown to differ on the basis of symptom trajectories and risk-factor profiles is delineated.

Trajectories of functioning after remission from anxiety disorders: 2-year course and outcome predictors

In anxiety disorders, symptom remission is accompanied by improvements in functioning but significant functional impairments may persist because of co-morbid disorders, lower functioning prior to the onset of the anxiety disorder or residual subthreshold anxiety symptoms.