Anxiety disorders

@article{Craske2017AnxietyD,
  title={Anxiety disorders},
  author={Michelle G. Craske and Murray B. Stein and Thalia C. Eley and Mohammed R. Milad and Andrew Holmes and Ronald M. Rapee and Hans-Ulrich Wittchen},
  journal={Nature Reviews Disease Primers},
  year={2017},
  volume={3}
}
Anxiety disorders constitute the largest group of mental disorders in most western societies and are a leading cause of disability. The essential features of anxiety disorders are excessive and enduring fear, anxiety or avoidance of perceived threats, and can also include panic attacks. Although the neurobiology of individual anxiety disorders is largely unknown, some generalizations have been identified for most disorders, such as alterations in the limbic system, dysfunction of the… 
Prevention of Anxiety Disorders Across the Lifespan
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This issue of JAMA Psychiatry presents the first systematic review and meta-analysis examining the efficacy of prevention of anxiety disorders across the lifespan, and presents a common misconception that anxiety disorders are reserved for the “worried well” and represent a personality flaw rather than a disorder.
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TLDR
It is concluded that common genetic variation accounts for a substantive proportion of the genetic architecture underlying anxiety.
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TLDR
It is indicated that sex may not be a major index of neurodevelopmental genetic heterogeneity, that is captured by ADHD PRS and rare CNV burden, in adults with anxiety and depression.
Generalized Anxiety and Panic Symptoms in the German National Cohort (NAKO).
  • A. Erhardt, G. Gelbrich, J. Deckert
  • Psychology, Medicine
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
  • 2021
TLDR
Clinically relevant GAD symptoms as well as panic attacks are frequent in the NAKO, are associated with sociodemographic factors and high anxiety symptoms are accompanied by pronounced stress and depression levels.
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TLDR
Although the amount and quality of the evidence for most risk/protective factors for anxiety and obsessive-compulsive disorders is limited, a number of factors significantly increase the risk for these disorders, may have potential prognostic ability and inform prevention.
Investigating gender-specific effects of familial risk for attention-deficit hyperactivity disorder and other neurodevelopmental disorders in the Swedish population
TLDR
Results provide modest support for the possibility that familial/genetic risks for ADHD may show gender-specific phenotypic expression, and there could be gender- specific biases in diagnoses of anxiety and ADHD.
A Diagnostic-Oriented Screening Scale for Anxiety Disorders: The Center for Epidemiologic Studies Anxiety Scale (CESA)
TLDR
The main findings suggest that the CESA is useful for screening for anxiety in general (alpha coefficient of 0.83), as well as for the four common anxiety disorders.
Molecular Basis Underlying the Therapeutic Potential of Vitamin D for the Treatment of Depression and Anxiety
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The main mechanisms that may underlie the potential antidepressant and anxiolytic effects of vitamin D are highlighted and preclinical and clinical studies that support the therapeutic potential of this vitamin for the management of these disorders are discussed.
Shared genetic etiology between anxiety disorders and psychiatric and related intermediate phenotypes
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It is suggested that common genetic variants underlying the risk of anxiety disorders contribute to elevated risks of MDD, SCZ, ADHD and neuroticism and reduced quality of life, putamen volume and cognitive performance.
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TLDR
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