Anucleate platelets generate progeny.

@article{Schwertz2010AnucleatePG,
  title={Anucleate platelets generate progeny.},
  author={Hansj{\"o}rg Schwertz and Sarah K{\"o}ster and Walter H A Kahr and Noemi Michetti and Bjoern F. Kraemer and David A. Weitz and Robert C Blaylock and Larry W. Kraiss and Andreas Greinacher and Guy A. Zimmerman and Andrew S. Weyrich},
  journal={Blood},
  year={2010},
  volume={115 18},
  pages={3801-9}
}
Platelets are classified as terminally differentiated cells that are incapable of cellular division. However, we observe that anucleate human platelets, either maintained in suspension culture or captured in microdrops, give rise to new cell bodies packed with respiring mitochondria and alpha-granules. Platelet progeny formation also occurs in whole blood cultures. Newly formed platelets are structurally indistinguishable from normal platelets, are able to adhere and spread on extracellular… CONTINUE READING
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Regulating the eukaryotic cell cycle

  • H Lodish, CA Kaiser, M Krieger
  • Ahr K, Ed. Molecular Cell Biology (6th ed)
  • 2008

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