Antiviral therapy of herpes simplex and varicella-zoster virus infections.

  title={Antiviral therapy of herpes simplex and varicella-zoster virus infections.},
  author={Peter Wutzler},
  volume={40 5-6},
Antiviral treatment of herpesvirus infections is rapidly changing since the advent of new drugs with improved oral availability. The efficacy of valaciclovir, the prodrug of aciclovir, and famciclovir, the prodrug of penciclovir, in the treatment of herpes genitalis and acute herpes zoster has been well documented in large clinical trials. Both drugs are effective on zoster-associated pain. Brivudin and sorivudine which are the most active compounds against varicella-zoster virus (VZV) in cell… CONTINUE READING


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