Antiviral strategies combining antiretroviral drugs with RNAi-mediated attack on HIV-1 and cellular co-factors.

@article{Boutimah2013AntiviralSC,
  title={Antiviral strategies combining antiretroviral drugs with RNAi-mediated attack on HIV-1 and cellular co-factors.},
  author={Fatima Boutimah and Julia J. M. Eekels and Ying Liu and Ben Berkhout},
  journal={Antiviral research},
  year={2013},
  volume={98 1},
  pages={121-9}
}
To improve the care of HIV-1/AIDS patients there is a critical need to develop tools capable of blocking viral evolution and circumventing therapy-associated problems. An emerging solution is gene therapy either as a stand-alone approach or as an adjuvant to pharmacological drug regimens. Combinatorial RNAi by multiplexing antiviral RNAi inhibitors through vector-mediated delivery has recently shown significant superiority over conventional mono-therapies. Viral as well as cellular co-factor… CONTINUE READING

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Antiviral Research xxx

  • F. Boutimah
  • 2013
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