Antiviral instruction of bone marrow leukocytes during respiratory viral infections.

@article{Hermesh2010AntiviralIO,
  title={Antiviral instruction of bone marrow leukocytes during respiratory viral infections.},
  author={Tamar Hermesh and Bruno Moltedo and Thomas M. Moran and Carolina Ballester Lopez},
  journal={Cell host & microbe},
  year={2010},
  volume={7 5},
  pages={343-53}
}
Respiratory viral infections trigger a robust inflammatory response in the lung, producing cytokines, chemokines, and growth factors that promote infiltration of effector leukocytes. Whereas the role of chemokines and infiltrating leukocytes in antiviral immunity is well studied, the effect that lung cytokines have on leukocytes in distal hematopoietic and lymphoid tissues and their role in antiviral immunity is unknown. We show that, during infection with influenza or Sendai virus, the lung… CONTINUE READING