Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis.

@article{Swarup2007AntiviralAA,
  title={Antiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitis.},
  author={Vivek Swarup and Joydeep Ghosh and Soumya Sankar Ghosh and Amit Saxena and Anirban Basu},
  journal={Antimicrobial agents and chemotherapy},
  year={2007},
  volume={51 9},
  pages={3367-70}
}
Rosmarinic acid (RA) reduced the mortality of mice infected with Japanese encephalitis virus (JEV). Significant decreases in viral loads (P < 0.001) and proinflammatory cytokine levels (P < 0.001) were observed in JEV-infected animals treated with RA compared to levels in infected mice without treatment, at 8 to 9 days postinfection.