Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.

@article{Reymen1995AntiviralAO,
  title={Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.},
  author={D. Reymen and L. Naesens and J. Balzarini and A. Holý and H. Dvoř{\'a}kov{\'a} and E. De Clercq},
  journal={Antiviral research},
  year={1995},
  volume={28 4},
  pages={
          343-57
        }
}
Human herpesvirus 6 (HHV-6) was examined in vitro for its sensitivity to a broad range of nucleoside analogues, including acyclovir (ACV), ganciclovir (GCV), penciclovir (PCV), buciclovir (BCV), brivudin (BVDU), the N7-isomer of 6-deoxyganciclovir (S2242), foscarnet (phosphonoformic acid, PFA), and several acyclic nucleoside phosphonate (ANP) analogues such as (S)-HPMPA, (S)-HPMPC, PMEA and PMEDAP. Antiviral efficacy was monitored microscopically by the inhibitory effect of the compounds on HHV… Expand
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