Antiviral activity of metal chelates of caffeic acid and similar compounds towards herpes simplex, VSV‐Ebola pseudotyped and vaccinia viruses

@article{Langland2018AntiviralAO,
  title={Antiviral activity of metal chelates of caffeic acid and similar compounds towards herpes simplex, VSV‐Ebola pseudotyped and vaccinia viruses},
  author={J. Langland and B. Jacobs and C. Wagner and Guillermo G. Ruiz and T. Cahill},
  journal={Antiviral Research},
  year={2018},
  volume={160},
  pages={143–150}
}
ABSTRACT Organic compounds with a caffeoyl moiety (e.g. caffeic acid, rosmarinic acid, chicoric acid, etc.) have antiviral properties towards herpes simplex (HSV), influenza and immunodeficiency viruses (HIV). This study evaluated the HSV antiviral properties of caffeic acid when paired with a variety of metal and other inorganic ions. The results demonstrated that the antiviral activity of caffeic acid increased upwards of 100‐fold by the addition of cations, such as Fe3+, and anionic… Expand
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