Antiviral activity of conjugates between poly(L-lysine) and synthetic oligodeoxyribonucleotides.

Abstract

Short (14 to 20-mer range) synthetic oligodeoxyribonucleotides (oligos) allow to modulate specifically viral or cellular gene expression at various stages thus providing a versatile tool for fundamental studies and a rational approach to antiviral chemotherapy. Several problems, such as metabolic stability and efficient cell internalization of oligos, still… (More)

Topics

Cite this paper

@article{Leonetti1988AntiviralAO, title={Antiviral activity of conjugates between poly(L-lysine) and synthetic oligodeoxyribonucleotides.}, author={John P. Leonetti and Brian L. Rayner and Marc Lemaitre and Corinne Gagnor and Pierre G Milhaud and J. L. Imbach and Bernard Lebleu}, journal={Gene}, year={1988}, volume={72 1-2}, pages={323-32} }